Recent advances in recombinant adeno-associated virus (rAAV) gene therapy for choroideremia show gene replacement to be a promising approach.It is, however, well known that contact of vector solution with plastic materials in the surgical device may result in non-specific adsorption with resulting loss of physical titer and/or level of protein expr
Objective: To examine the efficacy of a fall prevention/management intervention among persons with multiple sclerosis (PwMS) who use a wheelchair (WC) or scooter full-time.Design: Pre-post/follow-up trial Setting: Community and research laboratory Participants: Twenty-one PwMS who used a WC or scooter full-time, self-reported at least 1 fall/12 mon
Plasma discharges in the tungsten (W) Environment Steady-state Tokamak (WEST) are strongly AMPLIFY CONDITIONER impacted by W contamination.In WEST experiments, due to W contamination, the power radiated in the plasma ( P _Rad ) is on average, around 50% of the total power injected into the plasma ( P _TOT ).Furthermore, this radiated power fraction
Retrovirus morphogenesis entails assembly of Gag proteins and the viral genome on the host plasma membrane, acquisition of the viral membrane and envelope proteins through budding, and formation of the core through the maturation process.Although in both immature and mature retroviruses, Gag and capsid proteins are organized as paracrystalline stru